ISLAMABAD -- Local media reported that at least five people were killed and four others were injured in a U.S. drone strike in Pakistan's northwest tribal region of North Waziristan Monday. According to the report by local Urdu TV channel Dunya, the strike came at about 1:00 a.m. (local time) when a U.S. drone targeted a house and a vehicle in Mir Ali area of North Waziristan, one of the seven semi-autonomous tribal areas along Pakistan-Afghanistan border. The U.S. drone fired four missiles. Residents said the death toll may rise further as the injured were in critical condition. Identities of the killed and injured people are not known yet. Some media reports said five drones are still hovering over the area, creating panic among the residents. Monday's drone strike is the 16th of its kind in Pakistan since the beginning of this year. To date, at least 117 people have reportedly been killed in such strikes in 2012.